Professor YE Xinshan, Professor JIA Yanxing and Professor JIAO Ning from School of Pharmaceutical Sciences, Peking University, visited the Lanzhou Institute of Chemical Physics (LICP), Chinese Academy of Sciences (CAS), on January 17. During their visit, they each delivered a lecture.

The title of Professor YE’s lecture is Chemical synthesis of oligosaccharide based on pre-activation strategy and some pharmaceutical discoveries based on sugar. In the lecture, Professor YE introduced the concept of oligosaccharide synthesis by pre-Activation strategy put forward by his group, one pot glycosylation based on pre-activation strategy and the application of the approach in the synthesis of biologically active oligosaccharides.

In his lecture entitled Total synthesis of several indole alkaloids, Professor JIA introduced his group’s progress in the total synthesis and biomimetic synthesis of natural products with important biological activity, structural modification of natural products with biological activity, the structure activity relationship, new methods in organic synthesis, etc.

Professor JIAO introduced some facile, highly efficient synthetic methods his group developed from simple raw materials and with oxygen as oxidants in his lecture entitled Highly Efficient Methodologies via Oxygenation and Nitrogenation.

Introduction to Professor YE Xinshan:

Education:

1981-1985 B.Sc., Chemistry, Wuhan University, Wuhan, China

1985-1988 M.Sc., Organic Chemistry, Wuhan University, Wuhan, China　　　　　　　　　 

1993-1996 Ph.D., Organic Chemistry, The Chinese University of Hong Kong, Hong Kong

1996-2000 Research Associate, The Scripps Research Institute, La Jolla, California, USA

Research Interests:

(1) Development of new methodologies or strategies for assembly of oligosaccharides;

(2) Synthesis and evaluation of biologically important oligosaccharides such as tumor-associated antigens;

(3) Chemical modifications of aminoglycoside antibiotics;

(4) Design, synthesis and evaluation of carbohydrate-processing enzyme inhibitors as well as discovery of new carbohydrate-based drugs.

Introduction to Professor JIA Yanxing:

Education:

2002-2007 Institut de Chimie des Substances Naturelles (ICSN), Centre National de la Recherche Scientifique (CNRS), France. Advisor: Professor Jieping Zhu

1997-2002 Ph.D., Organic Chemistry, Lanzhou University, Lanzhou, China. Advisor: Professor Yongqiang Tu 1993-1997B.Sc., Chemistry, Lanzhou University, Lanzhou, China

Research interests:

(1) Natural products total synthesis and biomimetic synthesis

(2) Synthetic medicinal chemistry

(3) Development of new synthetic methods

Introduction to Professor JIAO Ning:

Education:

1995-1999B.S. Organic Chemistry, Shandong University, Ji’nan, P. R. China 1999-2004Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences Ph D((Supervisor: Professor Shengming Ma))

Research interests:

(1)　 Aerobic oxidation & dioxygen activation

(2)　 Nitrogenation reactions

(3)　 Highly selective organic transformation

(4)　 Enzyme and protein hybrid catalysis