This research was based on the CEOP/CAMP-Tibet observed data at AWS (Automatic Weather Station) of MS3478 in the seasonal frozen soil region of northern Tibetan Plateau from March 2007 to February 2008. The variation characteristics of PE (potential evapotranspiration) were analyzed based on the Penman-Monteith method recommended by FAO (the Food and Agriculture Organization of the United Nations).The contributions of dynamic, thermal and water factors to PE were discussed, and the wet-dry condition of the plateau region was further studied. The results indicated that daily PE was between 0.52 mm and 6.46 mm for the whole year. Monthly PE was over 107 mm from May to September, but decreased to less than 41 mm from November to February. Annual PE was 1,037.8 mm. In the summer, thermal PE was significantly more than dynamic PE, but conversely in the winter. Annual variation of thermal PE was of sine wave pattern.In addition, drought and semi-drought climate lasted for a long time while semi-humid climate was short. The effect of water and dynamic factors on PE varied considerably with the seasons. Annual variation of thermal PE was of sine wave pattern.